SK-II's approach to skin care began with a Japanese scientist's observation of the youthful hands of sake brewery workers. That led to the development of Pitera, SK-II’s skin-loving galactomyces ferment filtrate ingredient derived from yeast. The premium Japanese beauty brand is renowned for its anti-aging skin care products that help restore the skin's natural 28-day renewal cycle. The famous SK-II Facial Treatment Essence contains 90% Pitera to refine skin, even skin tone and reduce fine lines and dark spots.